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In whom, in the judgment of the physician, treatment should be started with a beta-blocker rather than a diuretic. Propranolol is a competitive antagonist which specifically competes with beta-adrenergic receptor stimulating agents for available beta-receptor sites. Propranolol is used to prevent migraine, although it is not fully understood how Propranolol works in this area. Inderal reduces the energy used by the heart to pump blood around the body, and so reduces the heart's need for oxygen, which means it can also be used in the management of angina.

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