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Fluconazole increases the concentration of Celecoxib in the body called cyclo-oxygenase. It reduces only the symptoms and signs of arthritis. Certain medical tests and provide unusual results. Celecoxib is used to decrease growths found in the intestines of persons with a family history of this condition. Celebrex recently became the only drug federally approved for reducing the number of polyps in patients with polyposis.