Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system diseases due to the risk of neurological aggravation. It is important to maintain a constant level of Flagyl in the blood. Metronidazole is an antibiotic effective against anaerobic bacteria and certain parasites. It is important to maintain a constant level of Flagyl in the blood. Metronidazole is usually taken two or three times a day for ten days or longer. Metronidazole should not be used in the first trimester of pregnancy.
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