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If needed, the Effexor extended-release capsule may be carefully opened and the entire contents sprinkled on a spoonful of cool applesauce. One should use Effexor extended-release with caution in the elderly, since they may be more sensitive to its effects, There are several anti-depressants in the market and each has their own positive and negative attributes. If taken properly as per the doctor's instructions, can be a very effective anti-depressant medication. Families and caregivers must closely watch patients who take Effexor extended-release capsules.