Bupropion sustained-release is available as a pill that you take by mouth, and without meals. For depression and generic Wellbutrin. You have trouble sleeping, you may be taking your dose too close to bedtime. Your dose will probably be the lowest, taken two times a day. At least several months. Antidepressants, Bupropion hydrochloride tends to have a somewhat stimulating effect. Wellbutrin, originally developed as an anti-depressant, has been shown to work equally well for quitting smoking in people without a history of depression.
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