Metformin increases the sensitivity of muscle cells to insulin. Metformin can rarely cause a serious condition called lactic acidosis. Glucophage should be taken with meals. Glucophage should be taken with meals. Metformin can rarely cause a serious condition called lactic acidosis. Glucophage is used to control blood sugar levels. Metformin can rarely cause a serious condition called lactic acidosis. Metformin reduces the amount of glucose in the blood. Metformin comes as a tablet and an extended-release tablet to take by mouth.
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