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If Nexium gives you an allergic reaction, or you may require a dosage adjustment or special monitoring. Esomeprazole works best if taken on an empty stomach at least one hour before a meal. Nexium is usually taken once a day at least one hour before a meal. Esomeprazole reduce the production of acid in the stomach. Nexium is used to treat the symptoms of GERD and other conditions involving excessive stomach. For the majority of gastric ulcers. Nexium is used to treat and prevent stomach and intestinal ulcers, damage to the gastrointestinal tract caused by stomach acid or infection.
