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Azithromycin should not be taken at the same time as magnesium-based antacids because antacids will bind the Azithromycin and prevent it from being absorbed from the intestine. It has a prolonged half-life that allows for once a day dosing and also for short-term treatment courses for most infections. Clinical trials have shown that Azithromycin ought to be taken at the same time as antacids that contain aluminum or magnesium. In twenty persons who are treated with Azithromycin. Clinical trials have shown that Azithromycin ought to be taken at least one hour pending to or two hours following meals.
