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Glucophage lowers the amount of sugar produced by cells in the liver. Metformin decreases the amount of glucose in the blood. Glucophage is from the biguanide class of oral anti-hyperglycemic agents. Metformin also increases your body's proper response to the insulin you naturally produce, and by decreasing the amount of glucose made by your liver. Take by mouth. Take by mouth. Your medical condition and response to therapy. Glucophage should be taken with meals.

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