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Propranolol reduces the workload of the heart and so decreases its demand for oxygen. This medicine suddenly, particularly if you have ischemic heart disease. Treatment must always be initiated and individual titration of dosage carried out using the conventional tablets. Propranolol may increase oxygen requirements by increasing left ventricular fiber length, end diastolic pressure, and the velocity and extent of myocardial contraction. Possible deleterious effects from long-term use of Propranolol have not yet been adequately appraised.
