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Before taking Prednisolone, you should tell your doctor about all of your medical conditions and about all other medicines you are using. Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Prednisone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly.
