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By blocking the enzyme in the wall of the stomach that produces acid. Your body adjusts to the new medicine. Nexium capsules should be taken at least one hour before meals and at the same time every day. Nexium is available in a powdered intravenous formulation to be reconstituted for injection. Along with their useful effects Esomeprazole can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Esomeprazole capsules should be applied one hour before meals and at the same time every day. Your usual routine so that you do not forget to take it.