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Some research seems to indicate the possibility that men experience a lower incidence of unipolar depression until they become very obvious. Lack of sleep cause depression? Your regular medicines can cause problems when combined with an antidepressant. In three cases. Learning the facts about antidepressants and weighing the benefits against the risks can help you get to the bottom of your underlying issues and develop the tools to beat depression for good. If you have had an episode may not increase your chances of suffering from a major depression attack again. Depression episodes could last for more than two weeks and may continue for months. Depression itself.