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Ramp upof paroxetine: "Paroxetine can cause side effects that may impair your thinking or reactions. Research has shown that depression and anxiety disorders usually require long-term treatment because of their chronic nature and the risk of relapse. As selective serotonin reuptake inhibitors. It could take several weeks before you start feeling better. If your doctor has prescribed Paxil for you, you are now taking an FDA-approved medication proven safe and effective for long-term use and is well tolerated."